Onglyza? Somebody got paid to name this drug. Think about that for a while.
Saxagliptin (Onglyza) – Think DM2
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Monthly Archives: July 2009
Human Fatalities Caused by Cows
Yes, Anemia Matters
Mortality risk rose at least 41% with presence of anemia at age 85 and more than doubled with new-onset anemia thereafter
HTN Increases Lacunar Infarct Risk 60%
Both lacunar infarcts and white matter hyperintensities are considered structural markers of small vascular disease
Carcinogenic to Humans
Tanning beds have moved to the highest-risk cancer category of radiation sources in an update from the International Agency for Research on Cancer (IARC).
NT-proBNP – Find It, Post It
Here is a pretty good article on NT-proBNP.
Read it after you watch the video on giant killer squids.
Attack of the Giant Killer Squids – The Video
This is a blog about underwriting. But sometimes you have to give the people what they want. And they want more giant squids.
Biomarkers in NSTE-ACS
Prognostic Value of Biomarkers During and After Non–ST-Segment Elevation Acute Coronary Syndrome
Even during follow-up, NT-proBNP demonstrated the strongest association to the composite endpoint of death/myocardial infarction.
If I find a good article/tutorial on NT-proBNP I’ll post it.
Higher HgA1c = Lower HDL
CONCLUSIONS Poor glycemic control appears to be an independent risk factor for low HDL cholesterol in type 2 diabetes.
Another Fascinating U Shaped Mortality Curve
To look farther down the disease spectrum than the analysis in ACCORD, Dr. Aguilar’s group retrospectively examined outcomes for a national cohort of 5,815 ambulatory diabetic patients with established heart failure who were treated in ambulatory clinics at VA medical centers.
During two years of follow-up, mortality rates were:
* 25.0% in the bottom quintile with hemoglobin A1c levels of 6.4% or less.
* 23.0% in the group with A1c levels of 6.5% to 7.1%.
* 17.7% in the middle quintile with glycosylated hemoglobin levels above 7.1% but no more than 7.8%.
* 22.5% in the group with A1c levels of 7.9% to 9.0%.
* 23.2% in the top quartile with hemoglobin A1c levels above 9.0%.
This is must-have information for all the life settlement underwriters out there.
