OncoBriefs: Hookah Risk

OncoBriefs: Hookah Risk, Brain Cancer, Lung Cancer.

Urinary concentration of the benzene metabolite S-phenylmercapturic acid (SPMA) was more than four times greater in hookah smokers and two times greater in people exposed to secondhand hookah smoke, when compared with people who had no exposure. The findings put a damper on enthusiasm for hookah as a safer alternative to cigarettes, as reported online in Cancer Epidemiology, Biomarkers and Prevention.

JAMA – Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction

JAMA Network | JAMA | Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction.

Conclusions and Relevance  In this cohort of patients undergoing elective coronary angiography, nonobstructive CAD, compared with no apparent CAD, was associated with a significantly greater 1-year risk of MI and all-cause mortality. These findings suggest clinical importance of nonobstructive CAD and warrant further investigation of interventions to improve outcomes among these patients.

 

Snorting bupropion – The Poison Review

Snorting bupropion | The Poison Review.

The abuse of bupropion by pulverizing and snorting the medication has been described at least as far back as 2002. Bupropion inhibits re-uptake of dopamine and norepinephrine, but apparently has little or no effect on serotonin. It is abused for its psychotropic effects that resemble those of amphetamine and cocaine..

A hallmark of overdose with sustained-release or extended-release bupropion formulations is delayed onset of seizures — sometimes more than 8 hours after ingestion. When these preparations are crushed and insufflated, absorption is rapid and manifestations would be expected to come on more quickly.

- See more at: http://www.thepoisonreview.com/2014/11/12/snorting-bupropion/#sthash.35NLtujG.dpuf